2414629-94-8

2414629-94-8 structure

2414629-94-8 structure

Name: hCAIX/XII-IN-3
Chemical Name: hCAIX/XII-IN-3
CAS Number: 2414629-94-8
Molecular Formula: C₂₀H₁₃F₃N₂O₄
Molecular Weight: 402.32
Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
Create Date: 2022-08-23 13:37:14
Modify Date: 2024-01-10 09:42:58
hCAIX/XII-IN-3 (compound 6q) is a potent and selective hCAIX and hCAXIIinhibitor with Ki values of >10000, >10000, 66.2, 4.4 nM for hCAI, hCAII, hCAIX and hCAXII, respectively[1].

Name	hCAIX/XII-IN-3

Description	hCAIX/XII-IN-3 (compound 6q) is a potent and selective hCAIX and hCAXIIinhibitor with Ki values of >10000, >10000, 66.2, 4.4 nM for hCAI, hCAII, hCAIX and hCAXII, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	Ki: >10000 nM (hCAI); >10000 nM (hCAII); 66.2 nM (hCAIX); 4.4 nM (hCAXII)[1].
References	[1]. Thacker PS, et al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.

Molecular Formula	C₂₀H₁₃F₃N₂O₄
Molecular Weight	402.32