2414601-79-7

2414601-79-7 structure

2414601-79-7 structure

Name: hCAXII-IN-4
Chemical Name: hCAXII-IN-4
CAS Number: 2414601-79-7
Molecular Formula: C₂₂H₂₇N₅O₆S
Molecular Weight: 489.54
Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
Create Date: 2022-08-03 11:32:59
Modify Date: 2024-08-19 16:07:21
hCAXII-IN-4 (compound 5j) is a potent and selective CA XII inhibitor with an Ki value of 6.4 nM for human CA XII[1].

Name	hCAXII-IN-4

Description	hCAXII-IN-4 (compound 5j) is a potent and selective CA XII inhibitor with an Ki value of 6.4 nM for human CA XII[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	Ki: 129.8 nM (hCAI), 40.7 nM (hCAII), 45.3 nM (hCAIX), 6.4 nM (hCAXII)[1]
References	[1]. Moi D, et al. Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors. Bioorg Chem. 2020 May;98:103728.

Molecular Formula	C₂₂H₂₇N₅O₆S
Molecular Weight	489.54