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2414629-92-6

2414629-92-6 structure

2414629-92-6 structure

Name: hCAXII-IN-5
Chemical Name: hCAXII-IN-5
CAS Number: 2414629-92-6
Molecular Formula: C₂₃H₂₂N₂O₄
Molecular Weight: 390.43
Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
Create Date: 2022-08-25 12:33:38
Modify Date: 2024-04-09 13:43:28
hCAXII-IN-5 (compound 6o) is a potent and selective hCAXII inhibitor with Ki values of >10000, >10000, 286.1, 1.0 nM for hCAI, hCAII, hCAIX and hCAXII, respectively[1].

Name	hCAXII-IN-5

Description	hCAXII-IN-5 (compound 6o) is a potent and selective hCAXII inhibitor with Ki values of >10000, >10000, 286.1, 1.0 nM for hCAI, hCAII, hCAIX and hCAXII, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	Ki: >10000 nM (hCAI); >10000 nM (hCAII); 286.1 nM (hCAIX); 1.0 nM (hCAXII)[1].
References	[1]. Thacker PS, et al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.

Molecular Formula	C₂₃H₂₂N₂O₄
Molecular Weight	390.43

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