2418576-06-2

2418576-06-2 structure

Name: mEH-IN-1
Chemical Name: mEH-IN-1
CAS Number: 2418576-06-2
Molecular Formula: C₁₆H₁₇F₆NOS
Molecular Weight: 385.37
Catalog: Research Areas Cancer
Create Date: 2022-09-02 10:00:02
Modify Date: 2024-09-07 18:17:00
mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian α/β-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer[1].

Name	mEH-IN-1

Description	mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian α/β-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Cardiovascular Disease Research Areas >> Neurological Disease
References	[1]. Bogdan Barnych, et al. Development of potent inhibitors of the human microsomal epoxide hydrolase. Eur J Med Chem. 2020 May 1;193:112206.

Molecular Formula	C₁₆H₁₇F₆NOS
Molecular Weight	385.37