mEH-IN-1

Modify Date: 2024-09-07 18:17:00

mEH-IN-1 Structure
mEH-IN-1 structure
Common Name mEH-IN-1
CAS Number 2418576-06-2 Molecular Weight 385.37
Density N/A Boiling Point N/A
Molecular Formula C16H17F6NOS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of mEH-IN-1


mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian α/β-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer[1].

 Names

Name mEH-IN-1

 mEH-IN-1 Biological Activity

Description mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian α/β-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer[1].
Related Catalog
References

[1]. Bogdan Barnych, et al. Development of potent inhibitors of the human microsomal epoxide hydrolase. Eur J Med Chem. 2020 May 1;193:112206.

 Chemical & Physical Properties

Molecular Formula C16H17F6NOS
Molecular Weight 385.37
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