1610537-25-1

1610537-25-1 structure

Name: Metallo-β-lactamase-IN-8
Chemical Name: Metallo-β-lactamase-IN-8
CAS Number: 1610537-25-1
Molecular Formula: C₁₃H₁₁ClN₂O₄S
Molecular Weight: 326.76
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2022-08-15 17:33:41
Modify Date: 2024-01-14 18:28:05
Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity[1].

Name	Metallo-β-lactamase-IN-8

Description	Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Li JQ, et, al. Hydroxamic acid with benzenesulfonamide: An effective scaffold for the development of broad-spectrum metallo-β-lactamase inhibitors. Bioorg Chem. 2020 Dec;105:104436.

Molecular Formula	C₁₃H₁₁ClN₂O₄S
Molecular Weight	326.76