Metallo-β-lactamase-IN-8

Modify Date: 2024-01-14 18:28:05

Metallo-β-lactamase-IN-8 structure	Common Name	Metallo-β-lactamase-IN-8
	CAS Number	1610537-25-1	Molecular Weight	326.76
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₁₁ClN₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Metallo-β-lactamase-IN-8

Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity[1].

Name	Metallo-β-lactamase-IN-8

Description	Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Li JQ, et, al. Hydroxamic acid with benzenesulfonamide: An effective scaffold for the development of broad-spectrum metallo-β-lactamase inhibitors. Bioorg Chem. 2020 Dec;105:104436.

Molecular Formula	C₁₃H₁₁ClN₂O₄S
Molecular Weight	326.76

Metallo-β-lactamase-IN-8

Use of Metallo-β-lactamase-IN-8

Names

Metallo-β-lactamase-IN-8 Biological Activity

Chemical & Physical Properties