557-09-5

MOLECULAR WEIGHT :

351.83

WISWESSER LINE NOTATION :

OV7 2 &-ZN-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

9 gm/kg

TOXIC EFFECTS :

Behavioral - food intake (animal) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea

REFERENCE :

JHEMA2 Journal of Hygiene, Epidemiology, Microbiology, and Immunology. (Avicenum, Malostranske namesti 28, 11802 Prague 1, Czechoslovakia) V.1- 1957- Volume(issue)/page/year: 18,144,1974

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intratracheal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

9 mg/kg

TOXIC EFFECTS :

Behavioral - food intake (animal) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea

REFERENCE :

JHEMA2 Journal of Hygiene, Epidemiology, Microbiology, and Immunology. (Avicenum, Malostranske namesti 28, 11802 Prague 1, Czechoslovakia) V.1- 1957- Volume(issue)/page/year: 18,144,1974

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2370 mg/kg

TOXIC EFFECTS :

Behavioral - food intake (animal) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea

REFERENCE :

JHEMA2 Journal of Hygiene, Epidemiology, Microbiology, and Immunology. (Avicenum, Malostranske namesti 28, 11802 Prague 1, Czechoslovakia) V.1- 1957- Volume(issue)/page/year: 18,144,1974 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

104 mg/m3/4H/40D-I

TOXIC EFFECTS :

Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Metabolism (Intermediary) - other proteins

REFERENCE :

JHEMA2 Journal of Hygiene, Epidemiology, Microbiology, and Immunology. (Avicenum, Malostranske namesti 28, 11802 Prague 1, Czechoslovakia) V.1- 1957- Volume(issue)/page/year: 18,144,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83596 No. of Facilities: 579 (estimated) No. of Industries: 18 No. of Occupations: 34 No. of Employees: 14197 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83596 No. of Facilities: 1408 (estimated) No. of Industries: 18 No. of Occupations: 21 No. of Employees: 26378 (estimated) No. of Female Employees: 5525 (estimated)