Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PARP1-IN-11
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Purity: 98.0%
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2482484-87-5

2482484-87-5 structure

2482484-87-5 structure

Name: PARP1-IN-11
Chemical Name: PARP1-IN-11
CAS Number: 2482484-87-5
Molecular Formula: C₁₆H₁₂N₂O₄
Molecular Weight: 296.28
Catalog: Signaling Pathways Cell Cycle/DNA Damage PARP
Create Date: 2022-09-04 20:00:51
Modify Date: 2024-04-08 13:51:35
PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC50 value of 0.082 µM. PARP1-IN-11 shows complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1 and TNKS2[1].

Name	PARP1-IN-11

Description	PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC50 value of 0.082 µM. PARP1-IN-11 shows complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1 and TNKS2[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	PARP1:0.082 μM (IC50) PARP2 TNKS1 TNKS2
References	[1]. Shao X, et al. Synthesis of 2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide and 3-oxo-3,4-dihydrobenzo[b][1,4]oxazine-8-carboxamide derivatives as PARP1 inhibitors. Bioorg Chem. 2020 Sep;102:104075.

Molecular Formula	C₁₆H₁₂N₂O₄
Molecular Weight	296.28

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