2648851-27-6

2648851-27-6 structure

Name: PD-1/PD-L1-IN-18
Chemical Name: PD-1/PD-L1-IN-18
CAS Number: 2648851-27-6
Molecular Formula: C₃₃H₃₂BrCl₂N₃O₄
Molecular Weight: 685.43
Catalog: Signaling Pathways Immunology/Inflammation PD-1/PD-L1
Create Date: 2022-08-04 14:32:10
Modify Date: 2025-08-21 00:44:38
PD-1/PD-L1-IN-18 (Compound L31) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-18 blocks PD-1/PD-L1 with the IC50 of 1.054 μM. Antitumor Activity[1].

Name	PD-1/PD-L1-IN-18

Description	PD-1/PD-L1-IN-18 (Compound L31) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-18 blocks PD-1/PD-L1 with the IC50 of 1.054 μM. Antitumor Activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1
References	[1]. Liu Liu, et al. Syntheses, Biological Evaluations, and Mechanistic Studies of Benzo[ c][1,2,5]oxadiazole Derivatives as Potent PD-L1 Inhibitors with In Vivo Antitumor Activity. J Med Chem. 2021 Jun 24;64(12):8391-8409.

Molecular Formula	C₃₃H₃₂BrCl₂N₃O₄
Molecular Weight	685.43