PD-1/PD-L1-IN-18

Modify Date: 2024-01-10 04:45:26

PD-1/PD-L1-IN-18 Structure
PD-1/PD-L1-IN-18 structure
Common Name PD-1/PD-L1-IN-18
CAS Number 2648851-27-6 Molecular Weight 685.43
Density N/A Boiling Point N/A
Molecular Formula C33H32BrCl2N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PD-1/PD-L1-IN-18


PD-1/PD-L1-IN-18 (Compound L31) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-18 blocks PD-1/PD-L1 with the IC50 of 1.054 μM. Antitumor Activity[1].

 Names

Name PD-1/PD-L1-IN-18

 PD-1/PD-L1-IN-18 Biological Activity

Description PD-1/PD-L1-IN-18 (Compound L31) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-18 blocks PD-1/PD-L1 with the IC50 of 1.054 μM. Antitumor Activity[1].
Related Catalog
References

[1]. Liu Liu, et al. Syntheses, Biological Evaluations, and Mechanistic Studies of Benzo[ c][1,2,5]oxadiazole Derivatives as Potent PD-L1 Inhibitors with In Vivo Antitumor Activity. J Med Chem. 2021 Jun 24;64(12):8391-8409.

 Chemical & Physical Properties

Molecular Formula C33H32BrCl2N3O4
Molecular Weight 685.43