2439168-72-4

2439168-72-4 structure
2439168-72-4 structure
  • Name: PIM1-IN-7
  • Chemical Name: PIM1-IN-7
  • CAS Number: 2439168-72-4
  • Molecular Formula: C23H23N5O
  • Molecular Weight: 385.46
  • Catalog: Signaling Pathways JAK/STAT Signaling Pim
  • Create Date: 2022-08-15 21:06:42
  • Modify Date: 2024-01-09 20:33:23
  • PIM1-IN-7 (compound 6c) is a potent PIM-1 inhibitor, with an IC50 of 0.67 μM. PIM1-IN-7 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 42.9 and 7.68 μM, respectively[1].

Name PIM1-IN-7
Description PIM1-IN-7 (compound 6c) is a potent PIM-1 inhibitor, with an IC50 of 0.67 μM. PIM1-IN-7 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 42.9 and 7.68 μM, respectively[1].
Related Catalog
Target

PIM1:0.67 μM (IC50)

References

[1]. Philoppes JN, et al. New pyrazolopyrimidine derivatives with anticancer activity: Design, synthesis, PIM-1 inhibition, molecular docking study and molecular dynamics. Bioorg Chem. 2020 Jul;100:103944.

Molecular Formula C23H23N5O
Molecular Weight 385.46
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