PIM1-IN-7

Modify Date: 2025-08-28 16:24:35

PIM1-IN-7 structure	Common Name	PIM1-IN-7
	CAS Number	2439168-72-4	Molecular Weight	385.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₃N₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PIM1-IN-7

PIM1-IN-7 (compound 6c) is a potent PIM-1 inhibitor, with an IC50 of 0.67 μM. PIM1-IN-7 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 42.9 and 7.68 μM, respectively[1].

Name	PIM1-IN-7

Description	PIM1-IN-7 (compound 6c) is a potent PIM-1 inhibitor, with an IC50 of 0.67 μM. PIM1-IN-7 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 42.9 and 7.68 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> Pim
Target	PIM1:0.67 μM (IC50)
References	[1]. Philoppes JN, et al. New pyrazolopyrimidine derivatives with anticancer activity: Design, synthesis, PIM-1 inhibition, molecular docking study and molecular dynamics. Bioorg Chem. 2020 Jul;100:103944.

Molecular Formula	C₂₃H₂₃N₅O
Molecular Weight	385.46

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