103628-62-2

103628-62-2 structure

Name: Sumatriptan hydrochloride
Chemical Name: Sumatriptan hydrochloride
CAS Number: 103628-62-2
Molecular Formula: C₁₄H₂₂ClN₃O₂S
Molecular Weight: 331.86
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2022-08-05 05:37:19
Modify Date: 2024-01-02 15:50:08
Sumatriptan (GR 43175) hydrochloride is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan hydrochloride can be used for migraine headache research[1][2].

Name	Sumatriptan hydrochloride

Description	Sumatriptan (GR 43175) hydrochloride is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan hydrochloride can be used for migraine headache research[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT1D Receptor:17 nM (Ki) 5-HT1B Receptor:27 nM (Ki) 5-HT1A Receptor:100 nM (Ki)
References	[1]. S J Peroutka, et al. Sumatriptan (GR 43175) interacts selectively with 5-HT1B and 5-HT1D binding sites. Eur J Pharmacol. 1989 Apr 12;163(1):133-6. [2]. K L Dechant, et al. Sumatriptan. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the acute treatment of migraine and cluster headache. Drugs. 1992 May;43(5):776-98.

Molecular Formula	C₁₄H₂₂ClN₃O₂S
Molecular Weight	331.86