Sumatriptan hydrochloride

Modify Date: 2024-01-02 15:50:08

Sumatriptan hydrochloride Structure
Sumatriptan hydrochloride structure
 Common Name Sumatriptan hydrochloride
CAS Number 103628-62-2 Molecular Weight 331.86
Density N/A Boiling Point N/A
Molecular Formula C14H22ClN3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Sumatriptan hydrochloride


Sumatriptan (GR 43175) hydrochloride is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan hydrochloride can be used for migraine headache research[1][2].

 Names

Name Sumatriptan hydrochloride

 Sumatriptan hydrochloride Biological Activity

Description Sumatriptan (GR 43175) hydrochloride is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan hydrochloride can be used for migraine headache research[1][2].
Related Catalog
Target

5-HT1D Receptor:17 nM (Ki)

5-HT1B Receptor:27 nM (Ki)

5-HT1A Receptor:100 nM (Ki)

References

[1]. S J Peroutka, et al. Sumatriptan (GR 43175) interacts selectively with 5-HT1B and 5-HT1D binding sites. Eur J Pharmacol. 1989 Apr 12;163(1):133-6.

[2]. K L Dechant, et al. Sumatriptan. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the acute treatment of migraine and cluster headache. Drugs. 1992 May;43(5):776-98.

 Chemical & Physical Properties

Molecular Formula C14H22ClN3O2S
Molecular Weight 331.86
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