2493298-68-1

2493298-68-1 structure
2493298-68-1 structure
  • Name: Topoisomerase II inhibitor 8
  • Chemical Name: Topoisomerase II inhibitor 8
  • CAS Number: 2493298-68-1
  • Molecular Formula: C14H8N4O3S
  • Molecular Weight: 312.30
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Topoisomerase
  • Create Date: 2022-08-17 18:20:12
  • Modify Date: 2024-01-12 12:37:45
  • Topoisomerase II inhibitor 8 (compound 22) is a potent topoisomerase II inhibitor, with an IC50 of 0.52 μM. Topoisomerase II inhibitor 8 exhibits good anti-proliferative activities and can arrest the cell cycle at G2/M phase[1].

Name Topoisomerase II inhibitor 8
Description Topoisomerase II inhibitor 8 (compound 22) is a potent topoisomerase II inhibitor, with an IC50 of 0.52 μM. Topoisomerase II inhibitor 8 exhibits good anti-proliferative activities and can arrest the cell cycle at G2/M phase[1].
Related Catalog
Target

Topoisomerase II:0.52 μM (IC50)

References

[1]. Abbass EM, et, al. Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers. Bioorg Chem. 2020 Nov;104:104255.

Molecular Formula C14H8N4O3S
Molecular Weight 312.30
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.