Topoisomerase II inhibitor 8

Modify Date: 2024-01-12 12:37:45

Topoisomerase II inhibitor 8 Structure
Topoisomerase II inhibitor 8 structure
Common Name Topoisomerase II inhibitor 8
CAS Number 2493298-68-1 Molecular Weight 312.30
Density N/A Boiling Point N/A
Molecular Formula C14H8N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Topoisomerase II inhibitor 8


Topoisomerase II inhibitor 8 (compound 22) is a potent topoisomerase II inhibitor, with an IC50 of 0.52 μM. Topoisomerase II inhibitor 8 exhibits good anti-proliferative activities and can arrest the cell cycle at G2/M phase[1].

 Names

Name Topoisomerase II inhibitor 8

 Topoisomerase II inhibitor 8 Biological Activity

Description Topoisomerase II inhibitor 8 (compound 22) is a potent topoisomerase II inhibitor, with an IC50 of 0.52 μM. Topoisomerase II inhibitor 8 exhibits good anti-proliferative activities and can arrest the cell cycle at G2/M phase[1].
Related Catalog
Target

Topoisomerase II:0.52 μM (IC50)

References

[1]. Abbass EM, et, al. Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers. Bioorg Chem. 2020 Nov;104:104255.

 Chemical & Physical Properties

Molecular Formula C14H8N4O3S
Molecular Weight 312.30
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