1093268-63-3

1093268-63-3 structure

Name: β-S-ARCA
Chemical Name: β-S-ARCA
CAS Number: 1093268-63-3
Molecular Formula: C₂₂H₃₁N₁₀O₁₇P₃S
Molecular Weight: 832.52
Catalog: Research Areas Others
Create Date: 2022-08-18 18:44:44
Modify Date: 2024-04-06 16:56:23
β-S-ARCA is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines[1].

Name	β-S-ARCA

Description	β-S-ARCA is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Warminski M, et al. Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect. ACS Chem Biol. 2021 Feb 19;16(2):334-343.

Molecular Formula	C₂₂H₃₁N₁₀O₁₇P₃S
Molecular Weight	832.52