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2787582-75-4

2787582-75-4 structure

2787582-75-4 structure

Name: Anticancer agent 77
Chemical Name: Anticancer agent 77
CAS Number: 2787582-75-4
Molecular Formula: C₂₅H₃₀BrN₇
Molecular Weight: 508.46
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-09-24 19:38:04
Modify Date: 2024-01-02 15:58:43
Anticancer agent 77 (Compound 6c) shows anticancer activity, and can be widely used in synthesis and medicinal chemistry research[1].

Name	Anticancer agent 77

Description	Anticancer agent 77 (Compound 6c) shows anticancer activity, and can be widely used in synthesis and medicinal chemistry research[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Anticancer agent 77 (0-1 μM) can inhibit the proliferation of breast cancer cells[1]. Anticancer agent 77 (0-1 μM; 24 h) can induce the apoptosis of breast cancer cells[1]. Cell Proliferation Assay[1] Cell Line: breast cancer cells Concentration: 0, 0.3, and 1 μM Incubation Time: Result: Decreased the number of EdU positive cells in breast cancer in a concentration-dependent manner. Apoptosis Analysis[1] Cell Line: breast cancer cells Concentration: 0, 0.3, and 1 μM Incubation Time: 24 hour Result: Promoted the apoptosis of breast cancer cells compared with the control group.
References	[1]. Jun Xiong, et al. Synthesis of 4-Tetrazolyl-Substituted 3,4-Dihydroquinazoline Derivatives with Anticancer Activity via a One-Pot Sequential Ugi-Azide/Palladium-Catalyzed Azide-Isocyanide Cross-Coupling/Cyclization Reaction. J Org Chem. 2022 Aug 5;87(15):9488-9496.

Molecular Formula	C₂₅H₃₀BrN₇
Molecular Weight	508.46

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