2772655-86-2
2772655-86-2 structure
- Name: CB1/2 agonist 3
- Chemical Name: CB1/2 agonist 3
- CAS Number: 2772655-86-2
- Molecular Formula: C25H41NO2
- Molecular Weight: 387.60
- Catalog: Signaling Pathways GPCR/G Protein Cannabinoid Receptor
- Create Date: 2022-09-02 10:05:20
- Modify Date: 2024-01-12 10:37:40
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CB1/2 agonist 3 (compound 52), a potent non-selective cannabinoid ligand, is a CB1/CB2 (cannabinoid receptor) competitive agonist. CB1/2 agonist 3 acts on hCB1 and hCB2 with Ki values of 5.9 nM and 3.5 nM, respectively[1].
| Name | CB1/2 agonist 3 |
|---|
| Description | CB1/2 agonist 3 (compound 52), a potent non-selective cannabinoid ligand, is a CB1/CB2 (cannabinoid receptor) competitive agonist. CB1/2 agonist 3 acts on hCB1 and hCB2 with Ki values of 5.9 nM and 3.5 nM, respectively[1]. |
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| Related Catalog | |
| Target |
hCB1-R:5.9 nM (Ki) hCB2-R:3.5 nM (Ki) |
| In Vitro | CB1/2 agonist 3 (compound 52) can partially induce [35S]GTPγS binding to hCB1-CHO cell membranes with an EC50 value of 30.99 nM, and slightly inhibit [35S]GTPγS binding to hCB2-CHO cell membranes with a mean EC50 value of 1.28 nM[1]. CB1/2 agonist 3 (compound 52) ((1 μM, 1 h) has antagonistic effect on CB1/CB2 agonist CP-55940 with a Kb value of 78.17 nM[1]. |
| References |
| Molecular Formula | C25H41NO2 |
|---|---|
| Molecular Weight | 387.60 |