Shanghai Nianxing Industrial Co., Ltd
China
Product Name: exarafenib
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2639957-39-2

2639957-39-2 structure

2639957-39-2 structure

Name: Exarafenib
Chemical Name: Exarafenib
CAS Number: 2639957-39-2
Molecular Formula: C₂₆H₃₄F₃N₅O₃
Molecular Weight: 521.58
Catalog: Signaling Pathways MAPK/ERK Pathway p38 MAPK
Create Date: 2022-08-31 18:23:31
Modify Date: 2026-07-01 19:01:01
Exarafenib (RAF/KIN_2787) is a potent, orally active pan-RAF inhibitor. Exarafenib has anticancer activity by suppression of downstream MAPK pathway signaling. Exarafenib can be used for cancer research[1][2].

Name	Exarafenib
Synonyms	(S)-N-(3-(2-(((R)-1-Hydroxypropan-2-yl)amino)-6-morpholinopyridin-4-yl)-4-methylphenyl)-3-(2,2,2-trifluoroethyl)pyrrolidine-1-cboxamide 1-Pyrrolidinecboxamide, N-[3-[2-[[(1R)-2-hydroxy-1-methylethyl]amino]-6-(4-morpholinyl)-4-pyridinyl]-4-methylphenyl]-3-(2,2,2-trifluoroethyl)-, (3S) exafenib

Description	Exarafenib (RAF/KIN_2787) is a potent, orally active pan-RAF inhibitor. Exarafenib has anticancer activity by suppression of downstream MAPK pathway signaling. Exarafenib can be used for cancer research[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Signaling Pathways >> MAPK/ERK Pathway >> Raf
References	[1]. Miller N, et, al. Antitumor activity of KIN-2787, a next-generation pan-RAF inhibitor, in combination with MEK inhibition in preclinical models of human NRAS mutant melanoma.2022 Jun 2;40(16): e15099. [2]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical

Molecular Formula	C₂₆H₃₄F₃N₅O₃
Molecular Weight	521.58

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