1258391-29-5

1258391-29-5 structure

1258391-29-5 structure

Name: HG-7-85-01-NH2
Chemical Name: HG-7-85-01-NH2
CAS Number: 1258391-29-5
Molecular Formula: C₂₇H₂₇F₃N₆OS
Molecular Weight: 540.60
Catalog: Research Areas Others
Create Date: 2022-10-17 09:29:06
Modify Date: 2024-01-03 19:23:21
HG-7-85-01-NH2 is the ligand of SNIPER(ABL)-033. SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 value of 0.3 μM[1].

Name	HG-7-85-01-NH2

Description	HG-7-85-01-NH2 is the ligand of SNIPER(ABL)-033. SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 value of 0.3 μM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Molecular Formula	C₂₇H₂₇F₃N₆OS
Molecular Weight	540.60