245747-10-8

245747-10-8 structure

245747-10-8 structure

Name: IL-2-IN-1
Chemical Name: IL-2-IN-1
CAS Number: 245747-10-8
Molecular Formula: C₁₇H₁₂F₆N₄O₂
Molecular Weight: 418.29
Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
Create Date: 2022-09-10 09:24:24
Modify Date: 2024-04-03 14:31:45
IL-2-IN-1 is a potent IL-2 inhibitor with an IC50 value of 1978 nM. IL-2-IN-1 shows antiproliferative activities[1].

Name	IL-2-IN-1

Description	IL-2-IN-1 is a potent IL-2 inhibitor with an IC50 value of 1978 nM. IL-2-IN-1 shows antiproliferative activities[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology
Target	IL-2:1978 nM (IC50)
In Vitro	IL-2-IN-1 (compound 2) shows antiproliferative activities with IC50s of 340, 1266 nM for human PBMC and rat PBMC, respectively[1].
References	[1]. Djuric SW, et al. 3,5-Bis(trifluoromethyl)pyrazoles: a novel class of NFAT transcription factor regulator. J Med Chem. 2000 Aug 10;43(16):2975-81.

Molecular Formula	C₁₇H₁₂F₆N₄O₂
Molecular Weight	418.29