676594-38-0

676594-38-0 structure

676594-38-0 structure

Name: JNK-IN-11
Chemical Name: JNK-IN-11
CAS Number: 676594-38-0
Molecular Formula: C₁₂H₁₁NO₃S₂
Molecular Weight: 281.35
Catalog: Signaling Pathways MAPK/ERK Pathway JNK
Create Date: 2022-09-01 19:45:18
Modify Date: 2024-04-06 00:15:04
JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease[1].

Name	JNK-IN-11

Description	JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> MAPK/ERK Pathway >> JNK
Target	JNK1:1.8 μM (IC50) JNK3:2.2 μM (IC50) JNK2:21.4 μM (IC50)
References	[1]. Hom RK, et al. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7303-7.

Molecular Formula	C₁₂H₁₁NO₃S₂
Molecular Weight	281.35