JNK-IN-11

Modify Date: 2024-04-06 00:15:04

JNK-IN-11 Structure
JNK-IN-11 structure
Common Name JNK-IN-11
CAS Number 676594-38-0 Molecular Weight 281.35
Density N/A Boiling Point N/A
Molecular Formula C12H11NO3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JNK-IN-11


JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease[1].

 Names

Name JNK-IN-11

 JNK-IN-11 Biological Activity

Description JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease[1].
Related Catalog
Target

JNK1:1.8 μM (IC50)

JNK3:2.2 μM (IC50)

JNK2:21.4 μM (IC50)

References

[1]. Hom RK, et al. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7303-7.

 Chemical & Physical Properties

Molecular Formula C12H11NO3S2
Molecular Weight 281.35