Shanghai Nianxing Industrial Co., Ltd
China
Product Name: MC-VA-PABC-MMAE
Price: Check
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: MC-VA-PABC-MMAE
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

1818864-51-5

1818864-51-5 structure

1818864-51-5 structure

Name: MC-VA-PABC-MMAE
Chemical Name: MC-VA-PABC-MMAE
CAS Number: 1818864-51-5
Molecular Formula: C₆₅H₉₉N₉O₁₄
Molecular Weight: 1230.53
Catalog: Research Areas Cancer
Create Date: 2022-09-29 21:32:12
Modify Date: 2025-08-27 05:05:28
MC-VA-PABC-MMAE is a drug-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1][2].

Name	MC-VA-PABC-MMAE

Description	MC-VA-PABC-MMAE is a drug-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1][2].
Related Catalog	Research Areas >> Cancer
Target	Auristatin
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Wang Y, et al. Development of applicable thiol-linked antibody-drug conjugates with improved stability and therapeutic index. Drug Deliv. 2022 Dec;29(1):754-766. [2]. Cazzamalli S, et al. Linker stability influences the anti-tumor activity of acetazolamide-drug conjugates for the therapy of renal cell carcinoma. J Control Release. 2017 Jan 28;246:39-45.

Molecular Formula	C₆₅H₉₉N₉O₁₄
Molecular Weight	1230.53

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.