MC-VA-PABC-MMAE

Modify Date: 2024-01-13 21:43:30

MC-VA-PABC-MMAE Structure
MC-VA-PABC-MMAE structure
Common Name MC-VA-PABC-MMAE
CAS Number 1818864-51-5 Molecular Weight 1230.53
Density N/A Boiling Point N/A
Molecular Formula C65H99N9O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MC-VA-PABC-MMAE


MC-VA-PABC-MMAE is a drug-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1][2].

 Names

Name MC-VA-PABC-MMAE

 MC-VA-PABC-MMAE Biological Activity

Description MC-VA-PABC-MMAE is a drug-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1][2].
Related Catalog
Target

Auristatin

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Wang Y, et al. Development of applicable thiol-linked antibody-drug conjugates with improved stability and therapeutic index. Drug Deliv. 2022 Dec;29(1):754-766.

[2]. Cazzamalli S, et al. Linker stability influences the anti-tumor activity of acetazolamide-drug conjugates for the therapy of renal cell carcinoma. J Control Release. 2017 Jan 28;246:39-45.

 Chemical & Physical Properties

Molecular Formula C65H99N9O14
Molecular Weight 1230.53
Top Suppliers:I want be here


Get all suppliers and price by the below link:

MC-VA-PABC-MMAE suppliers

MC-VA-PABC-MMAE price