1627136-54-2

1627136-54-2 structure
1627136-54-2 structure
  • Name: RSK2-IN-3
  • Chemical Name: RSK2-IN-3
  • CAS Number: 1627136-54-2
  • Molecular Formula: C24H26N4O5
  • Molecular Weight: 450.49
  • Catalog: Signaling Pathways MAPK/ERK Pathway Ribosomal S6 Kinase (RSK)
  • Create Date: 2022-08-31 16:34:05
  • Modify Date: 2024-09-18 11:42:07
  • RSK2-IN-3 (Compound 26) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase[1].

Name RSK2-IN-3
Description RSK2-IN-3 (Compound 26) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase[1].
Related Catalog
Target

RSK2:8.3 (pIC50, ERK2-MSK1 cascade)

RSK2:9.2 (pIC50, MSK1 CTKD)

References

[1]. Hall A, et al. Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1. ACS Med Chem Lett. 2022 Jun 25;13(7):1099-1108.

Molecular Formula C24H26N4O5
Molecular Weight 450.49
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