RSK2-IN-3

Modify Date: 2024-09-18 11:42:07

Use of RSK2-IN-3

RSK2-IN-3 (Compound 26) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase[1].

Name	RSK2-IN-3

Description	RSK2-IN-3 (Compound 26) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> Ribosomal S6 Kinase (RSK)
Target	RSK2:8.3 (pIC50, ERK2-MSK1 cascade) RSK2:9.2 (pIC50, MSK1 CTKD)
References	[1]. Hall A, et al. Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1. ACS Med Chem Lett. 2022 Jun 25;13(7):1099-1108.

Molecular Formula	C₂₄H₂₆N₄O₅
Molecular Weight	450.49