2409178-86-3

2409178-86-3 structure

2409178-86-3 structure

Name: SARS 3CLpro-IN-1
Chemical Name: SARS 3CLpro-IN-1
CAS Number: 2409178-86-3
Molecular Formula: C₂₂H₃₈N₄O₂
Molecular Weight: 390.56
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2022-09-10 14:29:19
Modify Date: 2024-03-30 19:54:16
SARS 3CLpro-IN-1 (Compound 3b) is a SARS 3CL protease inhibitor with an IC50 value of 95 μM, as a specific stereo isomerof the octahydroisochromene scaffold, directs the P1 site imidazole[1].

Name	SARS 3CLpro-IN-1

Description	SARS 3CLpro-IN-1 (Compound 3b) is a SARS 3CL protease inhibitor with an IC50 value of 95 μM, as a specific stereo isomerof the octahydroisochromene scaffold, directs the P1 site imidazole[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Anti-infection >> SARS-CoV
Target	IC50: 95 μM (SARS 3CL protease) [1]
In Vitro	SARS 3CLpro-IN-1 (Compound 3b) has high active (IC50=95 μM) and had a (1S, 3S)-configuration in the ring system[1].
References	[1]. Shin-Ichiro Yoshizawa, et al. Evaluation of an octahydroisochromene scaffold used as a novel SARS 3CL protease inhibitor. Bioorg Med Chem. 2020 Feb 15;28(4):115273.

Molecular Formula	C₂₂H₃₈N₄O₂
Molecular Weight	390.56