Shanghai Nianxing Industrial Co., Ltd
China
Product Name: FAK-IN-7
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

19948-85-7

19948-85-7 structure

19948-85-7 structure

Name: FAK-IN-7
Chemical Name: N-(5-(p-Tolyl)-1,3,4-thiadiazol-2-yl)benzamide
CAS Number: 19948-85-7
Molecular Formula: C₁₆H₁₃N₃OS
Molecular Weight: 295.36
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FAK
Create Date: 2022-09-13 06:27:47
Modify Date: 2025-09-02 13:05:07
FAK-IN-7 (compound 5r) is a FAK inhibitor (IC50=11.72 µM). FAK-IN-7 has good anti-proliferative activity and can be used in cancer research[1].

Name	N-(5-(p-Tolyl)-1,3,4-thiadiazol-2-yl)benzamide
Synonyms	MFCD00660411

Description	FAK-IN-7 (compound 5r) is a FAK inhibitor (IC50=11.72 µM). FAK-IN-7 has good anti-proliferative activity and can be used in cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FAK
Target	FAK:11.72 μM (IC50)
In Vitro	FAK-IN-7 (0-10 µM; 48 h) inhibits MCF-7 and B16-F10 cells proliferation[1]. Cell Proliferation Assay[1] Cell Line: MCF-7 and B16-F10 cells Concentration: 0-10 µM Incubation Time: 48 h Result: Exhibited anti-proliferative activity against MCF-7 and B16-F10 cells with IC50 values of 3.57 and 3.52 µM, respectively.
References	[1]. Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20(9):2789-95.

Molecular Formula	C₁₆H₁₃N₃OS
Molecular Weight	295.36

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.