FAK-IN-7

Modify Date: 2025-09-02 13:05:07

FAK-IN-7 Structure
FAK-IN-7 structure
Common Name FAK-IN-7
CAS Number 19948-85-7 Molecular Weight 295.36
Density N/A Boiling Point N/A
Molecular Formula C16H13N3OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FAK-IN-7


FAK-IN-7 (compound 5r) is a FAK inhibitor (IC50=11.72 µM). FAK-IN-7 has good anti-proliferative activity and can be used in cancer research[1].

 Names

Name N-(5-(p-Tolyl)-1,3,4-thiadiazol-2-yl)benzamide
Synonym More Synonyms

 FAK-IN-7 Biological Activity

Description FAK-IN-7 (compound 5r) is a FAK inhibitor (IC50=11.72 µM). FAK-IN-7 has good anti-proliferative activity and can be used in cancer research[1].
Related Catalog
Target

FAK:11.72 μM (IC50)

In Vitro FAK-IN-7 (0-10 µM; 48 h) inhibits MCF-7 and B16-F10 cells proliferation[1]. Cell Proliferation Assay[1] Cell Line: MCF-7 and B16-F10 cells Concentration: 0-10 µM Incubation Time: 48 h Result: Exhibited anti-proliferative activity against MCF-7 and B16-F10 cells with IC50 values of 3.57 and 3.52 µM, respectively.
References

[1]. Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20(9):2789-95.

 Chemical & Physical Properties

Molecular Formula C16H13N3OS
Molecular Weight 295.36

 Synonyms

MFCD00660411
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