2785430-84-2
2785430-84-2 structure
- Name: ALK5-IN-28
- Chemical Name: ALK5-IN-28
- CAS Number: 2785430-84-2
- Molecular Formula: C25H27N7
- Molecular Weight: 425.53
- Catalog: Signaling Pathways Stem Cell/Wnt TGF-beta/Smad
- Create Date: 2022-10-07 17:52:43
- Modify Date: 2025-08-26 20:49:28
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ALK5-IN-28 (compound Ex-05) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-28 has the potential to inhibit growth of tumour in vivo. ALK5-IN-28 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1].
| Name | ALK5-IN-28 |
|---|
| Description | ALK5-IN-28 (compound Ex-05) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-28 has the potential to inhibit growth of tumour in vivo. ALK5-IN-28 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1]. |
|---|---|
| Related Catalog | |
| Target |
ALK5:≤10 nM (IC50) |
| References |
[1]. Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent WO2022126133A1. |
| Molecular Formula | C25H27N7 |
|---|---|
| Molecular Weight | 425.53 |