Name | ALK5-IN-28 |
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Description | ALK5-IN-28 (compound Ex-05) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-28 has the potential to inhibit growth of tumour in vivo. ALK5-IN-28 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1]. |
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Related Catalog | |
Target |
ALK5:≤10 nM (IC50) |
References |
[1]. Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent WO2022126133A1. |
Molecular Formula | C25H27N7 |
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Molecular Weight | 425.53 |