Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ARD-69
Price:
Purity: 99.0%
Stocking Period: 10 Day
Contact: Huang

DC Chemicals Limited
China
Product Name: ARD-69
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao

2316837-10-0

2316837-10-0 structure

2316837-10-0 structure

Name: ARD-69
Chemical Name: ARD-69
CAS Number: 2316837-10-0
Molecular Formula: C₆₂H₇₄ClFN₈O₇S
Molecular Weight: 1129.82
Catalog: Signaling Pathways PROTAC PROTAC
Create Date: 2022-10-15 20:30:16
Modify Date: 2024-09-21 06:30:01
ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader. ARD-69 induces degradation of androgen receptor (AR) protein in AR-positive prostate cancer cell lines. ARD-69 suppresses AR-regulated gene expression[1].

Name	ARD-69

Description	ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader. ARD-69 induces degradation of androgen receptor (AR) protein in AR-positive prostate cancer cell lines. ARD-69 suppresses AR-regulated gene expression[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> Others >> Androgen Receptor
Target	Androgen receptor (AR)[1] PROTAC[1]
References	[1]. Han X, et al. Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer. J Med Chem. 2019 Jan 10.

Molecular Formula	C₆₂H₇₄ClFN₈O₇S
Molecular Weight	1129.82