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2316837-10-0

2316837-10-0 structure
2316837-10-0 structure
  • Name: ARD-69
  • Chemical Name: ARD-69
  • CAS Number: 2316837-10-0
  • Molecular Formula: C62H74ClFN8O7S
  • Molecular Weight: 1129.82
  • Catalog: Signaling Pathways PROTAC PROTAC
  • Create Date: 2022-10-15 20:30:16
  • Modify Date: 2024-09-21 06:30:01
  • ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader. ARD-69 induces degradation of androgen receptor (AR) protein in AR-positive prostate cancer cell lines. ARD-69 suppresses AR-regulated gene expression[1].
Name ARD-69
Description ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader. ARD-69 induces degradation of androgen receptor (AR) protein in AR-positive prostate cancer cell lines. ARD-69 suppresses AR-regulated gene expression[1].
Related Catalog
Target

Androgen receptor (AR)[1] PROTAC[1]

References

[1]. Han X, et al. Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer. J Med Chem. 2019 Jan 10.
Molecular Formula C62H74ClFN8O7S
Molecular Weight 1129.82
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title: CAS No. 2316837-10-0 | Chemsrc address: https://m.chemsrc.com/en/baike/1719631.html

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