1709815-23-5
1709815-23-5 structure
- Name: Emapalumab
- Chemical Name: Emapalumab
- CAS Number: 1709815-23-5
- Molecular Formula:
- Molecular Weight:
- Catalog: Signaling Pathways Immunology/Inflammation IFNAR
- Create Date: 2022-10-08 06:55:02
- Modify Date: 2025-09-12 09:55:36
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Emapalumab (NI-0501) is a humanized monoclonal IgG1 antibody that noncompetitively inhibits IFN-γ. Emapalumab binds with high affinity (Kd= 1.4 pM) to both free IFN-γ as well as IFN-γ bound to its receptor. Emapalumab can be used in research of hemophagocytic lymphohistiocytosis (HLH)[1].
| Name | Emapalumab |
|---|
| Description | Emapalumab (NI-0501) is a humanized monoclonal IgG1 antibody that noncompetitively inhibits IFN-γ. Emapalumab binds with high affinity (Kd= 1.4 pM) to both free IFN-γ as well as IFN-γ bound to its receptor. Emapalumab can be used in research of hemophagocytic lymphohistiocytosis (HLH)[1]. |
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| Related Catalog | |
| In Vitro | Emapalumab (NI-0501) impairs IFNcR1 and IFNc-Receptor-2 (IFNcR2) interaction induced by IFNc at the cell surface. |
| References |
| No Any Chemical & Physical Properties |