2389034-45-9

2389034-45-9 structure
2389034-45-9 structure
  • Name: HCAIX-IN-2
  • Chemical Name: HCAIX-IN-2
  • CAS Number: 2389034-45-9
  • Molecular Formula: C19H16N8O4S
  • Molecular Weight: 452.45
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
  • Create Date: 2022-11-01 17:18:13
  • Modify Date: 2024-04-06 12:21:12
  • HCAIX-IN-2 (compound 9d) is a selective carbonic anhydrase inhibitor with the Ki values of 24.6 nM and 45.3 nM for hCA IX and hCA XII, respectively[1].

Name HCAIX-IN-2
Description HCAIX-IN-2 (compound 9d) is a selective carbonic anhydrase inhibitor with the Ki values of 24.6 nM and 45.3 nM for hCA IX and hCA XII, respectively[1].
Related Catalog
Target

CA I:2481 nM (Ki)

hCA II:456.2 nM (Ki)

hCA IX:24.6 nM (Ki)

hCA XII:45.3 nM (Ki)

References

[1]. Mohamed A Said, et al. Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2020 Jan 1;185:111843.

Molecular Formula C19H16N8O4S
Molecular Weight 452.45
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