1539276-38-4

1539276-38-4 structure

Name: Plm IV inhibitor-2
Chemical Name: Plm IV inhibitor-2
CAS Number: 1539276-38-4
Molecular Formula: C₃₉H₅₄N₄O₄
Molecular Weight: 642.87
Catalog: Research Areas Infection
Create Date: 2022-10-22 17:14:02
Modify Date: 2024-01-27 10:56:01
Plm IV inhibitor-2 (compound 3) is a potent digestive vacuole plasmepsins IV (Plm IV) inhibitor with IC50 values of 24 nM, 70 nM and 0.3 μM for Plm IV, II and I, respectively. Plm IV inhibitor-2 can be used to research malaria caused by Plasmodium parasites[1].

Name	Plm IV inhibitor-2

Description	Plm IV inhibitor-2 (compound 3) is a potent digestive vacuole plasmepsins IV (Plm IV) inhibitor with IC50 values of 24 nM, 70 nM and 0.3 μM for Plm IV, II and I, respectively. Plm IV inhibitor-2 can be used to research malaria caused by Plasmodium parasites[1].
Related Catalog	Research Areas >> Infection
Target	Plm IV:24 nM (IC50) Plm II:70 nM (IC50) Plm I:0.3 μM (IC50)
References	[1]. Jaudzems K, et al. Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit. ACS Med Chem Lett. 2014 Jan 13;5(4):373-7.

Molecular Formula	C₃₉H₅₄N₄O₄
Molecular Weight	642.87