503860-51-3

503860-51-3 structure

Name: Shishijimicin B
Chemical Name: Shishijimicin B
CAS Number: 503860-51-3
Molecular Formula: C₄₅H₅₀N₄O₁₂S₃
Molecular Weight: 935.09
Catalog: Research Areas Cancer
Create Date: 2022-10-10 20:55:46
Modify Date: 2025-09-18 17:26:07
Shishijimicin B is an active compound of the enediyne class. Shishijimicin B shows extremely potent cytotoxicity with IC50 values of 2.0-3.3 nM. Shishijimicin B has antitumor activity and can be used for the research of cancer[1].

Name	Shishijimicin B

Description	Shishijimicin B is an active compound of the enediyne class. Shishijimicin B shows extremely potent cytotoxicity with IC50 values of 2.0-3.3 nM. Shishijimicin B has antitumor activity and can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 3.1 nM (3Y1 cells); 3.3 nM (Hela cells); 2.0 nM (P388 cells)[1]
In Vitro	Shishijimicin B (compound 2) has high cytotoxicity for 3Y1, Hela and P388 cells with IC50 values of 3.1 nM, 3.3 nM and 2.0 nM, respectively[1].
References	[1]. Naoya Oku, et al. Shishijimicins A-C, novel enediyne antitumor antibiotics from the ascidian Didemnum proliferum(1). J Am Chem Soc. 2003 Feb 26;125(8):2044-5.

Molecular Formula	C₄₅H₅₀N₄O₁₂S₃
Molecular Weight	935.09