Shanghai Nianxing Industrial Co., Ltd
China
Product Name: USP15-IN-1
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Purity: 99.81%
Stocking Period: 10 Day
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2260826-16-0

2260826-16-0 structure

2260826-16-0 structure

Name: USP15-IN-1
Chemical Name: USP15-IN-1
CAS Number: 2260826-16-0
Molecular Formula: C₂₂H₂₃N₃O₃
Molecular Weight: 377.44
Catalog: Signaling Pathways Cell Cycle/DNA Damage Deubiquitinase
Create Date: 2022-10-10 11:34:24
Modify Date: 2024-09-20 10:19:21
USP15-IN-1 is a potent USP15 inhibitor with an IC50 value of 3.76 μM. USP15-IN-1 can be used for researching anticancer[1].

Name	USP15-IN-1

Description	USP15-IN-1 is a potent USP15 inhibitor with an IC50 value of 3.76 μM. USP15-IN-1 can be used for researching anticancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase
Target	IC50: 3.76 μM (USP15)[1]
In Vitro	USP15-IN-1 (compound IM001) (0.001-5 μM; 48 h) exhibits highly anti-proliferative activity against non-small cell lung carcinoma and leukemia cells[1]. Cell Proliferation Assay[1] Cell Line: Non-small cell lung carcinoma and leukemia cells Concentration: 0.001 μM, 0.005 μM, 0.01 μM, 0.05 μM, 0.1 μM, 0.5 μM, 1 and 5 μM Incubation Time: 48 h Result: Exhibited highly anti-proliferative activity against non-small cell lung carcinoma and leukemia cells with IC50s of 1.94 μM and 2.22 μM.
References	[1]. Chen Yihua, et al. The tetrahydro-beta-carboline micromolecular organic compound and its derivative and medical usage of a kind of hydroxyl substitution. CN108727370A

Molecular Formula	C₂₂H₂₃N₃O₃
Molecular Weight	377.44

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