2842079-86-9
2842079-86-9 structure
- Name: SF-1 antagonist-1
- Chemical Name: SF-1 antagonist-1
- CAS Number: 2842079-86-9
- Molecular Formula: C22H18F4N6O3
- Molecular Weight: 490.41
- Catalog: Research Areas Cancer
- Create Date: 2022-11-11 22:04:06
- Modify Date: 2024-01-12 10:28:37
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SF-1 antagonist-1 (compound 11) is a antagonist of steroidogenic factor 1 (SF-1). SF-1 antagonist-1 affects SF-1 transcriptional activity with an EC50 value of ＜200 nM. SF-1 antagonist-1 inhibits the proliferation of Rat Leydig tumor cells. SF-1 antagonist-1 can be used for the research of cancer[1].
| Name | SF-1 antagonist-1 |
|---|
| Description | SF-1 antagonist-1 (compound 11) is a antagonist of steroidogenic factor 1 (SF-1). SF-1 antagonist-1 affects SF-1 transcriptional activity with an EC50 value of ＜200 nM. SF-1 antagonist-1 inhibits the proliferation of Rat Leydig tumor cells. SF-1 antagonist-1 can be used for the research of cancer[1]. |
|---|---|
| Related Catalog | |
| In Vitro | SF-1 antagonist-1 (0-20 μM) affects SF-1 transcriptional activity with an EC50 value of ＜200 nM[1]. SF-1 antagonist-1 (0-20 μM; 48 h) affects proliferation of R2C cells[1]. Cell Proliferation Assay[1] Cell Line: Rat Leydig tumor cell line, R2C Concentration: 0-20 μM Incubation Time: 48 h Result: Inhibited proliferation of R2C cells with an EC50 value of ＜200 nM. |
| References |
[1]. Raheja Neil, et al. PYRAZOLOPYRIMIDINONE COMPOUNDS. WO2022204481. 2022. |
| Molecular Formula | C22H18F4N6O3 |
|---|---|
| Molecular Weight | 490.41 |