Name | TH-Z145 |
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Description | TH-Z145, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 210 nM)[1]. |
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Related Catalog | |
Target |
FPPS[1] |
In Vivo | TH-Z145 (20 μg, i.p.) exhibits strong prophylactic effects in a pathogenic influenza model[1]. Animal Model: B16-OVA cells (s.c.) xenograft mice model[1]. Dosage: 20 μg Administration: Intraperitoneal injection (i.p.) Result: Inhibited tumor growth and prolonged survival. |
References |
Molecular Formula | C16H28O7P2 |
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Molecular Weight | 394.34 |