TH-Z145

Modify Date: 2024-04-08 20:08:43

TH-Z145 structure	Common Name	TH-Z145
	CAS Number	2260887-57-6	Molecular Weight	394.34
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₂₈O₇P₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TH-Z145

TH-Z145, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 210 nM)[1].

Name	TH-Z145

Description	TH-Z145, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 210 nM)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	FPPS[1]
In Vivo	TH-Z145 (20 μg, i.p.) exhibits strong prophylactic effects in a pathogenic influenza model[1]. Animal Model: B16-OVA cells (s.c.) xenograft mice model[1]. Dosage: 20 μg Administration: Intraperitoneal injection (i.p.) Result: Inhibited tumor growth and prolonged survival.
References	[1]. Xia Y, et al. The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery. Cell. 2018 Nov 1;175(4):1059-1073.e21.

Molecular Formula	C₁₆H₂₈O₇P₂
Molecular Weight	394.34

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TH-Z145
Price: Check
Purity: 98.29%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: TH-Z145
Price: ￥700.0/100mg ￥1200.0/250mg ￥2400.0/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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