2418022-85-0
2418022-85-0 structure
- Name: TMX-2164
- Chemical Name: TMX-2164
- CAS Number: 2418022-85-0
- Molecular Formula: C25H24ClFN6O6S
- Molecular Weight: 591.01
- Catalog: Signaling Pathways Apoptosis Bcl-2 Family
- Create Date: 2022-11-15 19:23:19
- Modify Date: 2024-01-10 20:12:48
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TMX-2164 is a potent, irreversible B-cell lymphoma 6 (BCL6) inhibitor with an IC50 value of 152 nM. TMX-2164 displays sustained target engagement and antiproliferative activity in cells[1].
| Name | TMX-2164 |
|---|
| Description | TMX-2164 is a potent, irreversible B-cell lymphoma 6 (BCL6) inhibitor with an IC50 value of 152 nM. TMX-2164 displays sustained target engagement and antiproliferative activity in cells[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 152 nM (BCL6)[1] |
| In Vitro | TMX-2164 (5 μM; 30 h; HEK293T-cells) displays sustained target engagement and to prolongs occupancy on BCL6 protein[1]. TMX-2164 (6.2 μM; 1, 3, and 5 d; SU-DHL-4 cells) exhibits single digit micromolar antiproliferative activity in SU-DHL-4 cells[1]. Cell Viability Assay[1] Cell Line: SU-DHL-4 cells Concentration: 6.2 μM Incubation Time: 1, 3, and 5 days Result: Inhibited cell growth with 5 days. |
| References |
| Molecular Formula | C25H24ClFN6O6S |
|---|---|
| Molecular Weight | 591.01 |