858097-86-6
858097-86-6 structure
- Name: TP-051
- Chemical Name: TP-051
- CAS Number: 858097-86-6
- Molecular Formula: C29H31FO6S
- Molecular Weight: 526.62
- Catalog: Signaling Pathways GPCR/G Protein GPR40
- Create Date: 2022-11-14 22:58:57
- Modify Date: 2024-01-06 16:23:00
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TP-051 is a potent FFAR1 agonist with an Ki value of 16 nM for human FFAR1. TP-051 can increase insulin secretion in rat insulinoma cells. TP-051 can be used to research type 2 diabetes[1].
| Name | TP-051 |
|---|
| Description | TP-051 is a potent FFAR1 agonist with an Ki value of 16 nM for human FFAR1. TP-051 can increase insulin secretion in rat insulinoma cells. TP-051 can be used to research type 2 diabetes[1]. |
|---|---|
| Related Catalog | |
| Target |
Ki: 16 nM (human FFAR1)[1] |
| In Vitro | TP-051 (compound 31) (0.01-10 μM; 2 h; INS-1 cells) augments insulin secretion in a dose-dependent manner in the presence of 11 mM glucose and statistically significant increases in insulin secretion were observed at doses of above 0.1 μM of the compound[1]. |
| References |
| Molecular Formula | C29H31FO6S |
|---|---|
| Molecular Weight | 526.62 |