2821749-58-8

2821749-58-8 structure

2821749-58-8 structure

Name: USP1-IN-3
Chemical Name: USP1-IN-3
CAS Number: 2821749-58-8
Molecular Formula: C₂₇H₂₄F₃N₇O
Molecular Weight: 519.52
Catalog: Research Areas Cancer
Create Date: 2022-11-22 11:57:44
Modify Date: 2024-01-02 16:44:10
USP1-IN-3 is a selective USPI inhibitor. USP1-IN-3 inhibits USPI-UAFI with an IC50 value of ＜30 nM. USP1-IN-3 can be used for the research of cancer[1].

Name	USP1-IN-3

Description	USP1-IN-3 is a selective USPI inhibitor. USP1-IN-3 inhibits USPI-UAFI with an IC50 value of ＜30 nM. USP1-IN-3 can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: ＜30 nM (USPI-UAFI)[1]
In Vitro	USP1-IN-3 has inhibitory against USPI-UAFI with an IC50 value of ＜30 nM[1]. USP1-IN-3 has viability for a non-isogenic pair of BRCAI mutant and BRCAI WT cell lines with IC50 values of ＜100 nM and ＞ 10 μM, respectively[1].
References	[1]. Scott Throner, et al. Pyrrolo[3,2-d]pyrimidine compounds and methods of use in the treatment of cancer. Patent. WO2022174184A1.

Molecular Formula	C₂₇H₂₄F₃N₇O
Molecular Weight	519.52