USP1-IN-3

Modify Date: 2024-01-02 16:44:10

USP1-IN-3 Structure
USP1-IN-3 structure
Common Name USP1-IN-3
CAS Number 2821749-58-8 Molecular Weight 519.52
Density N/A Boiling Point N/A
Molecular Formula C27H24F3N7O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of USP1-IN-3


USP1-IN-3 is a selective USPI inhibitor. USP1-IN-3 inhibits USPI-UAFI with an IC50 value of <30 nM. USP1-IN-3 can be used for the research of cancer[1].

 Names

Name USP1-IN-3

 USP1-IN-3 Biological Activity

Description USP1-IN-3 is a selective USPI inhibitor. USP1-IN-3 inhibits USPI-UAFI with an IC50 value of <30 nM. USP1-IN-3 can be used for the research of cancer[1].
Related Catalog
Target

IC50: <30 nM (USPI-UAFI)[1]

In Vitro USP1-IN-3 has inhibitory against USPI-UAFI with an IC50 value of <30 nM[1]. USP1-IN-3 has viability for a non-isogenic pair of BRCAI mutant and BRCAI WT cell lines with IC50 values of <100 nM and > 10 μM, respectively[1].
References

[1]. Scott Throner, et al. Pyrrolo[3,2-d]pyrimidine compounds and methods of use in the treatment of cancer. Patent. WO2022174184A1.

 Chemical & Physical Properties

Molecular Formula C27H24F3N7O
Molecular Weight 519.52