15641-17-5
15641-17-5 structure
- Name: Antiproliferative agent-16
- Chemical Name: WAY-313137
- CAS Number: 15641-17-5
- Molecular Formula: C17H15N3O
- Molecular Weight: 277.32
- Catalog: Research Areas Cancer
- Create Date: 2023-03-06 16:57:35
- Modify Date: 2024-01-10 19:39:35
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Antiproliferative agent-16 is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC50 of 6.94 μM for MCF-7 cells)[1].
| Name | WAY-313137 |
|---|---|
| Synonyms |
MFCD00412076
N'-[(E)-1H-Indol-3-ylmethylene]-2-phenylacetohydrazide Benzeneacetic acid, 2-[(1E)-1H-indol-3-ylmethylene]hydrazide |
| Description | Antiproliferative agent-16 is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC50 of 6.94 μM for MCF-7 cells)[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Antiproliferative agent-16 (compound 18f) 显示出对 DU145、LnCaP、MDA-MB231、MCF7 和 PaCa2 癌细胞的细胞毒性，IC50 值分别为 115.1 μM、51.63 μM、300.8 μM、6.94 μM、和 91.18 μM[1]。 |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C17H15N3O |
| Molecular Weight | 277.32 |
| Exact Mass | 277.121521 |
| LogP | 3.68 |
| Index of Refraction | 1.636 |