Antiproliferative agent-16

Modify Date: 2024-01-10 19:39:35

Antiproliferative agent-16 Structure
Antiproliferative agent-16 structure
Common Name Antiproliferative agent-16
CAS Number 15641-17-5 Molecular Weight 277.32
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C17H15N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antiproliferative agent-16


Antiproliferative agent-16 is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC50 of 6.94 μM for MCF-7 cells)[1].

 Names

Name WAY-313137
Synonym More Synonyms

 Antiproliferative agent-16 Biological Activity

Description Antiproliferative agent-16 is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC50 of 6.94 μM for MCF-7 cells)[1].
Related Catalog
In Vitro Antiproliferative agent-16 (compound 18f) 显示出对 DU145、LnCaP、MDA-MB231、MCF7 和 PaCa2 癌细胞的细胞毒性,IC50 值分别为 115.1 μM、51.63 μM、300.8 μM、6.94 μM、和 91.18 μM[1]。
References

[1]. Swapna Sundaree, et al. Synthesis and anticancer activity study of indolyl hydrazide-hydrazones. Med Chem Res 25, 941-950 (2016).

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Molecular Formula C17H15N3O
Molecular Weight 277.32
Exact Mass 277.121521
LogP 3.68
Index of Refraction 1.636

 Synonyms

MFCD00412076
N'-[(E)-1H-Indol-3-ylmethylene]-2-phenylacetohydrazide
Benzeneacetic acid, 2-[(1E)-1H-indol-3-ylmethylene]hydrazide