333357-56-5
333357-56-5 structure
- Name: HIF-1 inhibitor-4
- Chemical Name: WAY-299838
- CAS Number: 333357-56-5
- Molecular Formula: C18H19IN2O2
- Molecular Weight: 422.26013
- Catalog: Signaling Pathways Metabolic Enzyme/Protease HIF/HIF Prolyl-Hydroxylase
- Create Date: 2023-01-23 16:12:31
- Modify Date: 2024-04-05 18:15:55
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HIF-1 inhibitor-4 is a HIF-1 inhibitor (IC50: 560 nM). HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level[1].
| Name | WAY-299838 |
|---|---|
| Synonyms | Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)- |
| Description | HIF-1 inhibitor-4 is a HIF-1 inhibitor (IC50: 560 nM). HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level[1]. |
|---|---|
| Related Catalog | |
| In Vitro | HIF-1 inhibitor-4 (Compound 1) 抑制 HIF-1，IC50 为 560 nM (使用 U251 细胞进行定量，在 VEGF 启动子 (VEGF-PLAP) 的控制下表达 PLAP 报告基因)[1]。 |
| References |
| Molecular Formula | C18H19IN2O2 |
|---|---|
| Molecular Weight | 422.26013 |