6040-19-3

6040-19-3 structure

Name: Cucurbitacin A
Chemical Name: [(E,6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-9-(hydroxymethyl)-4,4,13,14-tetramethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
CAS Number: 6040-19-3
Molecular Formula: C₃₂H₄₆O₉
Molecular Weight: 574.70200
Catalog: Research Areas Cancer
Create Date: 2018-04-19 08:00:00
Modify Date: 2024-01-08 19:39:33
Cucurbitacin A, a triterpenoid that could be isolated from the Stems of Cucumis melo, shows anti-cancer activity[1].

Name	[(E,6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-9-(hydroxymethyl)-4,4,13,14-tetramethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
Synonyms	19-Norlanosta-5,23-diene-3,11,22-trione,25-(acetyloxy)-2,16,20-trihydroxy-9-(hydroxymethyl)-,(2beta,9beta,10alpha,16alpha,23E) Cucurbitacine A Cucurbitacin A

Description	Cucurbitacin A, a triterpenoid that could be isolated from the Stems of Cucumis melo, shows anti-cancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Cucurbitacin A inhibits the proliferation of A549 and BEL-7402 cells with IC50 values of 0.4 and 0.3 µM, respectively[1].
References	[1]. Chuan Chen, et al. Cucurbitane-type triterpenoids from the stems of Cucumis melo. J Nat Prod. 2009 May 22;72(5):824-9.

Hazard Codes	T